What is Silybum marianum used for?
Milk thistle contains compounds that may support skin, liver, and bone health and enhance weight loss. It may also be good for helping prevent insulin resistance. However, further research is necessary. Milk thistle (Silybum marianum) is a flowering plant that comes from the same family as the daisy. There’s conflicting research on the benefits of milk thistle for liver health. It may have protective effects on the liver, preventing damage. There’s some evidence that milk thistle can treat cirrhosis and chronic hepatitis, which can be caused by alcohol abuse, autoimmune disease, or viruses.Allergies: Those with known allergies to milk thistle or its components should avoid using silymarin supplements. Interactions with Medications: Silymarin may interact with certain medications, such as antidepressants, blood thinners, and immunosuppressants.The bottom line Milk thistle and probiotics are a good place to start. Avoid any supplement that contains a multitude of ingredients, or excessively high doses of those ingredients. They can actually be harmful to your liver.Research in the laboratory has shown that milk thistle might help to treat some liver diseases, such as hepatitis and cirrhosis. A few trials have looked at milk thistle for people with cancer. Trials have looked at silymarin (milk thistle) and chemotherapy.Silymarin, the active compound in milk thistle, has been extensively studied and shows that it is a safe and effective treatment for liver and kidney diseases.
What is the difference between silymarin and Silybum marianum?
Silymarin is the extract of Silybum marianum, or milk thistle, and consists of seven flavonoglignans (silibinin, isosilibinin, silychristin, isosilychristin and silydianin) and a flavonoid (taxifolin) [3]. Among these substances, silybin is mainly prevalent and has the most important biological effect. One study found that when patients with nonalcoholic fatty liver disease took milk thistle powder for eight weeks, they showed a major improvement in ultrasound fatty liver grading and liver enzymes, which are two key health indicators for fatty liver disease.Silymarin has antioxidant and anti-inflammatory properties. And it may help the liver repair itself by growing new cells. Although a number of animal studies demonstrate that milk thistle can be helpful in protecting the liver, results in human studies are mixed.Swelling (inflammation) of the liver (hepatitis). Research on the effects of milk thistle in people with hepatitis is not consistent. Some research shows that taking milk thistle extract by mouth for 4 weeks reduces hepatitis symptoms, such as dark urine and jaundice, but does not improve liver function tests.There’s no known interaction between milk thistle and omega-3 supplements. Taking them together may offer combined benefits for inflammation and liver health.
What are the side effects of Silybum marianum?
Side effects, which tend to be minor, can include bloating, nausea, and diarrhea. However, milk thistle may not be right for you if you’re pregnant, have diabetes, have specific hormone-sensitive health conditions (including some forms of breast cancer), or are allergic to the herb. Researchers say milk thistle is well tolerated by most people. And they suggest taking up to 700 mg of milk thistle three times per day for 24 weeks has been shown to be safe. Side effects are usually mild and may include symptoms like headaches, nausea and other stomach discomforts.If you take any medicines regularly, talk to your doctor before you start using milk thistle. It could interact with many drugs, including some that treat high cholesterol, infections, insomnia, and blood pressure.Milk thistle can be taken either in the morning or at night and can even be consumed on an empty stomach. However, taking milk thistle after a meal can help your stomach to digest it and is especially beneficial if you have a sensitive liver.Milk thistle may help reduce indigestion when taken with other supplements. Improve heart health. There’s evidence that milk thistle might help lower cholesterol and lower the risk of heart disease.It depends. Sometimes it can take up to 3 months for a milk thistle supplement to show its benefit. Our best advice is to stick with it, as it’ll benefit you in the long run for sure! As for milk thistle dosage for fatty liver, a 90-day study found that 250-376mg of milk thistle per day helped reduce liver fat.
What are the side effects of Silybum marianum?
Adverse effects associated with oral ingestion of milk thistle include: Gastrointestinal problems (e. Headache. If you have diabetes, use milk thistle with caution, since the supplement might lower blood sugar. There is also concern that milk thistle might affect estrogen levels. If you have breast cancer, uterine cancer, ovarian cancer, endometriosis or uterine fibroids, consider avoiding milk thistle.Drug Interactions with Milk Thistle may increase the effects of medications that decrease blood sugar levels (hypoglycemic medications) and may interfere with medications used to treat human immunodeficiency virus (HIV) infection (such as indinavir or saquinavir).If you have diabetes, use milk thistle with caution, since the supplement might lower blood sugar. There is also concern that milk thistle might affect estrogen levels. If you have breast cancer, uterine cancer, ovarian cancer, endometriosis or uterine fibroids, consider avoiding milk thistle.Adverse effects associated with oral ingestion of milk thistle include: Gastrointestinal problems (e. Headache.
Can silymarin damage the liver?
Results revealed that 65. The systematic review implies a potential advantageous influence of silymarin on liver enzyme levels, indicating its hepatoprotective potential. Conclusion. Silymarin improved ultrasound fatty liver grading and liver enzymes morbidly-obese patient candidates for bariatric surgery with NAFLD after only eight weeks, without any adverse effects.The results obtained indicate that silymarin seems to be effective in reducing the biochemical and ultrasonographic changes induced by non alcoholic fatty liver disease (NAFLD).Silymarin, during clinical trials, shows potential improvements in liver function, reduced mortality rates, and alleviation of symptoms across various liver disorders, with safety assessments showing low adverse effects.