What family is silymarin in?
Silymarin is a polyphenolic flavanoid derived from the milk thistle (Silybum marianum) which belongs to the Asteraceae family. Silymarin is the extract of Silybum marianum, or milk thistle, and consists of seven flavonoglignans (silibinin, isosilibinin, silychristin, isosilychristin and silydianin) and a flavonoid (taxifolin) [3]. Among these substances, silybin is mainly prevalent and has the most important biological effect.Researchers believe that a compound called silymarin in milk thistle has antioxidant, anti-inflammatory, and antiviral properties. Consequently, it may help prevent or treat various health conditions, including it might: Slow or prevent age-related decreases in brain function.
What is the difference between silymarin and Silybum?
Silymarin is the extract of Silybum marianum, or milk thistle, and consists of seven flavonoglignans (silibinin, isosilibinin, silychristin, isosilychristin and silydianin) and a flavonoid (taxifolin) [3]. Among these substances, silybin is mainly prevalent and has the most important biological effect. Side Effects of Silymarin Tablets Gastrointestinal discomforts, such as nausea, bloating, or diarrhoea. Loss of appetite. Headaches or dizziness. Allergic reactions, such as itching or skin rash.Clinically, silymarin reduces liver dysfunction, may reduce liver-related mortality in patients with cirrhosis and improves glycemic control in patients with concomitant diabetes, with few if any adverse events.
Can silymarin raise blood pressure?
Silymarin has protective effects against hypertension by reducing oxidative stress [[122], [123], [124]]. The oral dose of silymarin (300 mg/kg) for 8–12 days caused reduction of death rates in hypertensive rats. Silymarin inhibits the activation of microglia as well as the production of inflammatory mediators such as TNF-α and nitric oxide (NO), thus reducing damage to brain dopaminergic neurons. It has been documented in some studies that silymarin reduces the level of α-synuclein protein and increases the level of dopamine.
Is silymarin good for kidneys?
Recent evidence suggests that silymarin may be just as important for kidney health as for liver. Silymarin concentrates in kidney cells, where it aids in repairing and regeneration by increasing protein and nucleic acid synthesis. The results obtained indicate that silymarin seems to be effective in reducing the biochemical and ultrasonographic changes induced by non alcoholic fatty liver disease (NAFLD).Recent evidence suggests that silymarin may be just as important for kidney health as for liver. Silymarin concentrates in kidney cells, where it aids in repairing and regeneration by increasing protein and nucleic acid synthesis.