What are the side effects of taking andrographis?
Andrographis can cause side effects such as loss of appetite, diarrhea, vomiting, rash, headache, runny nose, and fatigue. When used in high doses or long-term, andrographis might cause swollen lymph glands, serious allergic reactions, elevations of liver enzymes, and other side effects. Another side effect to consider is the potential impact on the liver. Some studies suggest that high doses of andrographolide can lead to hepatotoxicity, which is toxic damage to the liver. Symptoms of liver damage can include jaundice (yellowing of the skin and eyes), dark urine, fatigue, and abdominal pain.An analysis of 26 cases of andrographolide-induced acute kidney injury (AKI) revealed that intravenous administration of the compound caused side effects such as lower back pain, decreased urine output, nausea, and vomiting (Zhang et al.
When should I take andrographis?
Double-blind trials have shown that common cold symptoms improve and recovery is faster when andrographis extract containing 48 to 60 mg andrographolides is taken in three or four divided doses daily, beginning as soon as possible after symptoms appear. Justicia paniculata Burm. Andrographis paniculata, commonly known as the King of Bitters, is named for its intensely bitter tasting leaves.Summary. Andrographis paniculata, commonly known as ‘king of bitters,’ is an herb traditionally used in Ayurveda and Traditional Chinese Medicine. Andrographis paniculata is used to treat the common cold. It is fairly effective when taken for three to five days after the symptoms first appear.
Is andrographis good for gut health?
Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity. Front Pharmacol. Apr 2:16:1536683. Results: Sixteen eligible in vivo animal studies showed that Andrographis paniculata extracts and isolated bioactive compounds have strong anti-inflammatory and antioxidant effects on cardiovascular diseases.In the United States, supplements made from this herb are used to relieve respiratory infections and inflammatory conditions. Andrographis supplements are made from the active part of the andrographis herb, called andrographolide. Andrographolide has anti-inflammatory and antibacterial properties.Andrographis is known botanically as Andrographis paniculata or by the synonym, Justicia paniculata. In the Indian medicinal herbs market it is often known by its Bengali name, kalmegh, or by its Hindi name kiryat.Andrographolide, a diterpenoid component found in traditional Chinese medicine Andrographis paniculata, is known as a natural antibiotic and can be used to treat inflammatory lesions of various systemic diseases.However, clinical reports have highlighted that andrographolide-based herbal injections may induce acute kidney injury and other renal adverse effects, thereby restricting its clinical application.